Clinical Trials

Chronic Obstructive Pulmonary Disease (COPD)

Posted on 9/23/2020
Chronic obstructive pulmonary disease (COPD) is a highly prevalent disease, associated with significant economic burden, and for which available standard-of-care therapies show insufficient treatment effect on symptoms, lung function, exacerbations and long term progression of the disease.

This study is designed to investigate the efficacy and safety profile of dupilumab over one year in patients with COPD who are in need of an additional treatment added to their current management and to assess the effect of the study drug on lung function, exacerbations and quality of life in patients with COPD.  The safety and tolerability of the study drug will also be monitored as part of the study.

The study will last about 68 weeks and you will have 19 visits to the clinic.  You will receive either the study drug or placebo (a substance that looks exactly like the study drug but has no active medicine).

You may qualify if you:
  • Are a current or former smoker with a smoking history of >10 pack-years
  • Mod-severe COPD for more than 12 months
  • History of signs/symptoms of chronic bronchitis (chronic productive cough) for 3 months in the past year
  • Do not have a history or diagnosis of asthma
  • Do not need oxygen more than 12 hours per day

There will be no charge for participating in the study.  The study medication, study materials and study specific visits will be provided at no charge to you or your insurance company. 

If you qualify and decide to participate you will be compensated for your time and travel while participating in the study.  

You will receive $75 for each study visit.  In the event you decide to have the study drug administered in the clinic, you will also receive $25 per visit for those administration visits.

Call our office for more information - (903) 238-8854
What Our Research Patients are Saying
Being able to participate in the COPD research study has been a life changing event for me.  This is an ongoing positive experience that has already made major differences in my health and the quality of my life. 
At the initial interview I was met by a team of friendly, caring, extremely knowledgeable and professional staff.  The high level of care and concern extended to me by the research doctor and everyone involved in this research study is phenomenal.  The research coordinator who I’ve been assigned to is simply “The Best”.  She answers and explains every question I have, she listens when I am having problems with my COPD, and offers helpful suggestions to get me through the rough spots.  She cheers me on when I need it most and follows up with phone calls to make certain I’m ok afterwards.
I’m amazed with the positive changes in my health from the first month of my participation. To cough is a rare occurrence where previously it was chronic…all day, every day.   Just walking short distances would render me breathless.  I now can walk longer, do more physically, and breathe much better.  I’m also not so tired all the time.  What a welcome change!
I’m happier, less fearful, and more confident in coping with COPD as a result of this research program.  If my participation can contribute to helping others cope with COPD that would be the absolutely ultimate outcome for me.  Thank you for allowing me this opportunity.     
~ S.T.

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